spams blacklist

[infolistas listas]

Hi users, is it possible to blacklist all domains and only allow some of
them add whitelist?(only receive mail from specific domains)
Is it possible to do that for specific users too?
Ex: user1 may  send mail to anyone but can only receive from some specific
domains
EX: user 2 may send mail to anyone and can receive mail from all domains
How can I optimise mailscanner and spamassassin , they where working well
until saterday when I began to receive lots of spam?

Thanks
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